When it comes to the causes of ALS, Stuart Millheiser can tell you that there is little in the way of solid information. Simply put, we do not know what causes this condition to arise, and it seems like there is no one who is at more risk than someone else. This is one of the reasons why research is done, and it seems like new information has come about in relation to this topic. Specifically, I would like to talk about the potential of genetics, as it relates to this condition.
Genetic Literacy Project put up an article that talked about ALS, and how roughly 90 percent of all cases have unknown points of origin. The other 19 percent or so, on the other hand, seem to be connected to genetics. The American Journal of Human Genetics talked about the gene known as C9orf72, and how mutations may work into how ALS development is carried out. The study that was mentioned in the article state that while the parents and grandparents of offspring did not have ALS, the offspring in question developed it.
Information such as this is interesting already, as I'm sure Stuart Millheiser and others can attest to. With that said, C9orf72 is typically found within the nuclear membrane of healthy neurons. When it comes to diseased neurons, according to the article mentioned earlier, C9orf72 is seen in the plasma membrane. What this means is that the element of protein is not nearly as prominent, which is essential for muscle growth and maintenance.
As you can clearly see, there are different variables which go into the risk and development of ALS alike. This isn't to say that the general public cannot help, as different methods can be taken up by the general public and activists such as Stuart Millheiser. For example, donations may be the most direct way to help, since the money will go to research. Given the extensive level of work that goes into this process, it's easy to see why financial backing matters.
I am sure that anyone can agree with the notion that information is nothing short of useful. Details like these are worthwhile, not only for those who are involved in science but those who consider themselves activists as well. For those who are part of the general public but would still like to help, it's easy to see that donations and the like can be offered. Considering the impact that ALS can have, any amount that's given can have a big impact.
Genetic Literacy Project put up an article that talked about ALS, and how roughly 90 percent of all cases have unknown points of origin. The other 19 percent or so, on the other hand, seem to be connected to genetics. The American Journal of Human Genetics talked about the gene known as C9orf72, and how mutations may work into how ALS development is carried out. The study that was mentioned in the article state that while the parents and grandparents of offspring did not have ALS, the offspring in question developed it.
Information such as this is interesting already, as I'm sure Stuart Millheiser and others can attest to. With that said, C9orf72 is typically found within the nuclear membrane of healthy neurons. When it comes to diseased neurons, according to the article mentioned earlier, C9orf72 is seen in the plasma membrane. What this means is that the element of protein is not nearly as prominent, which is essential for muscle growth and maintenance.
As you can clearly see, there are different variables which go into the risk and development of ALS alike. This isn't to say that the general public cannot help, as different methods can be taken up by the general public and activists such as Stuart Millheiser. For example, donations may be the most direct way to help, since the money will go to research. Given the extensive level of work that goes into this process, it's easy to see why financial backing matters.
I am sure that anyone can agree with the notion that information is nothing short of useful. Details like these are worthwhile, not only for those who are involved in science but those who consider themselves activists as well. For those who are part of the general public but would still like to help, it's easy to see that donations and the like can be offered. Considering the impact that ALS can have, any amount that's given can have a big impact.
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